A practical route for the highly stereoselective synthesis of tetrasubstituted fluoroalkenes.
نویسندگان
چکیده
A series of tetrasubstituted fluoroalkene derivatives were synthesized by the reaction of α-fluoro-β-carbonyl benzothiazol-2-yl sulfones with various nucleophiles in good yields with high stereoselectivities. The predominant cis configuration of fluorine and alkynyl groups was observed. A single isomer was obtained when a ketone, acetate or amide was used as the substrate in the presence of a base.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 3 شماره
صفحات -
تاریخ انتشار 2014